Born in Bombay, she is the daughter of a film producer, Chander Sadanah, and Seema Sadanah. She has two sisters, Nandita (Nagma), who is also an actress, Radhika (Roshni), and a younger brother Rahul. She has a Psychology Degree from Mithi Bai College of Arts, Bombay. She had dated Surya for over 4 years and married him on 11 September 2006. After the wedding, she announced her decision to stop acting. Jyothika is in family way and she's expecting her first baby in the month of August 2007.